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  • Approved Use: Aimovig® (erenumab-aooe) is a prescription medicine used for the preventive treatment of migraine in adults.

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I am...curious about side effects

Learn about the possible side effects of Aimovig®

Aimovig® was studied in 3 clinical trials* of approximately 2100 patients.

Everybody’s experience with Aimovig® is different. It’s important to talk to your doctor about whether Aimovig® is right for you and to learn about its possible side effects.

You shouldn’t take Aimovig® if you’re allergic to erenumab-aooe or any of the ingredients in Aimovig®. Allergic reactions, like rash or swelling, can happen hours to days after taking Aimovig®.

What were the common side effects in the first 3 months?

Side effects seen in at least 2% of patients on Aimovig® and at least 2% more common than those on placebo
Chart showing Aimovig® side effects in the first three months Chart showing Aimovig® side effects in the first three months

In clinical studies, the most common injection site reactions were pain, redness, and swelling.

†Injection site reactions include multiple adverse reactions described with related terms, such as injection site pain and injection site redness.

‡The rate of injection site reactions reported in this figure is with the prefilled syringe.

Side effects in the first 3 months Side effects in the first 3 months

Common side effects observed were injection site reactions, constipation, and cramps with muscle spasms.

Aimovig® may cause serious side effects, including allergic reactions, high blood pressure, and constipation with serious complications.

These are not all of the possible side effects of Aimovig®. Ask your pharmacist or doctor for more information. Call your doctor for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088. You may also report side effects to Amgen® at 1-800-77-AMGEN (1-800-772-6436).

Please see below for additional Important Safety Information.

*See the STRIVE, ARISE and LIBERTY trials for more information.

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Important Safety Information

Who should not use Aimovig®? Do not use Aimovig® if you are allergic to erenumab-aooe or any ingredients in Aimovig®. Before starting Aimovig®, tell your healthcare provider (HCP) about all your medical conditions, including if you have high blood pressure, have circulation problems in your fingers and toes, are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed. Tell your HCP about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.
 
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Important Safety Information

Who should not use Aimovig®? Do not use Aimovig® if you are allergic to erenumab-aooe or any ingredients in Aimovig®. Before starting Aimovig®, tell your healthcare provider (HCP) about all your medical conditions, including if you have high blood pressure, have circulation problems in your fingers and toes, are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed. Tell your HCP about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements. What are possible side effects of Aimovig®? Aimovig® may cause serious side effects, including:
  • Allergic reactions. Allergic reactions, including rash or swelling can happen after receiving Aimovig®. This can happen within hours to days after using Aimovig®. Call your HCP or get emergency medical help right away if you have any of the following symptoms of an allergic reaction: swelling of the face, mouth, tongue or throat, or trouble breathing.
  • Constipation with serious complications. Severe constipation can happen after receiving Aimovig®. In some cases people have been hospitalized or needed surgery. Contact your HCP if you have severe constipation or constipation associated with symptoms such as severe or constant belly pain, vomiting, swelling of belly or bloating.
  • High blood pressure. High blood pressure or worsening of high blood pressure can happen after receiving Aimovig®. Contact your healthcare provider if you have an increase in blood pressure.
  • Raynaud's Phenomenon. A type of circulation problem can worsen or happen after receiving AIMOVIG. Raynaud’s phenomenon can lead to your fingers or toes feeling numb, cool, or painful, or changing color from pale, to blue, to red. Contact your healthcare provider if these symptoms occur
The most common side effects of Aimovig® are pain, redness, or swelling at the injection site and constipation. These are not all of the possible side effects of Aimovig®. Call your HCP for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Click here for the full Prescribing Information and Patient Product Information.

APPROVED USE

Aimovig® (erenumab-aooe) is a prescription medicine used for the preventive treatment of migraine in adults.
References: 1. Parsabiv® (etelcalcetide) prescribing information, Amgen. 2. Data on file, Amgen; [Summary of Clinical Efficacy; 2015]. 3. Alexander ST, et al. Mol Pharmacol. 2015;88:853-865. 4. Data on file, Amgen; [Report R20130052, 2014]. 5. Chen P, et al. CPT Pharmacometrics Syst Pharmacol. 2016;5:484-494. 6. Sensipar® (cinacalcet) prescribing information, Amgen. 7. Ma JN, et al. J Pharmacol Exp Ther. 2011;337:275-284.
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Important Safety Information

Who should not use Aimovig? Do not use Aimovig if you are allergic to erenumab-aooe or any ingredients in Aimovig®