IMPORTANT SAFETY INFORMATION

Who should not use Aimovig^®?

Do not use Aimovig^® if you are allergic to erenumab-aooe or any ingredients in Aimovig^®.

Before starting Aimovig^®, tell your healthcare provider (HCP) about all your medical conditions, including if you are allergic to rubber or latex, pregnant or plan to become pregnant, breastfeeding or plan to breastfeed.

Tell your HCP about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

What are possible side effects of Aimovig^®?

Aimovig^® may cause serious side effects, including:

• Allergic reactions. Allergic reactions, including rash or swelling can happen after receiving Aimovig^®. This can happen within hours to days after using Aimovig®. Call your HCP or get emergency medical help right away if you have any of the following symptoms of an allergic reaction: swelling of the face, mouth, tongue or throat, or trouble breathing.

• Constipation with serious complications. Severe constipation can happen after receiving Aimovig^®. In some cases people have been hospitalized or needed surgery. Contact your HCP if you have severe constipation.

• High blood pressure. High blood pressure or worsening of high blood pressure can happen after receiving Aimovig^®. Contact your healthcare provider if you have an increase in blood pressure.

The most common side effects of Aimovig^® are pain, redness, or swelling at the injection site and constipation.

These are not all of the possible side effects of Aimovig^®. Call your HCP for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Click here for the full Prescribing Information and Patient Product Information.

APPROVED USE

Aimovig^® is a prescription medicine used for the preventive treatment of migraine in adults.